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PROTAC CB1R Degrader-1

CAT: 0013-GTR19275132-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19275132-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PROTACCB1R Degrader-1 is a potent and selective CB1R PROTAC degrader that employs the ubiquitin-proteasome system (UPS) to facilitate CB1R degradation, showing a DC50 of 3.37 μM in MCF-7 cells while exhibiting no effect on CB2R. It reduces CB1R-associated downstream signaling pathways (p-AKT, p-ERK, BCL2, and MCM5), thus inhibiting breast cancer cell proliferation and inducing apoptosis. PROTACCB1R Degrader-1 is applicable for breast cancer-related research.
Storage Conditions
-20°C
Notes
For research use only.

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