Aβ aggregation-IN-1

CAT: 0931-T204182-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T204182-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

352525-91-8

Target

Beta Amyloid

Related Pathways

Neuroscience

Bioactivity

Aβ aggregation-IN-1 (Compound 1b) is an inhibitor of amyloid-beta precursor protein. It suppresses the aggregation and disaggregation of amyloid-beta fibrils with IC50 values of 3.92 and 7.19 M, respectively. Additionally, Aβ aggregation-IN-1 reduces malondialdehyde formation in neuronal cells, increases intracellular levels of reduced glutathione (GSH), and inhibits caspase 3.

Smiles

C(F)(F)(F)C1=CC=C(/C=C/B(O)O)C=C1

Molecular Formula

C9H8BF3O2

Molecular Weight

215.965

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Aβ aggregation-IN-1

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