Aβ aggregation-IN-1

CAT: 0804-HY-W117986-01Size: 250 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0804-HY-W117986-01Size:250 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Description

Aβ aggregation-IN-1 (Compound 1b) is an amyloid-beta precursor protein inhibitor. Aβ aggregation-IN-1 inhibits amyloid-beta aggregation and disaggregation of fibrillogenesis with IC50 values of 3.92 and 7.19 M, respectively. Aβ aggregation-IN-1 also inhibits malondialdehyde formation, augments the intracellular reduced glutathione (GSH) levals and inhibits caspase 3 in neuronal cells[1].

CAS Number

352525-91-8

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Amyloid-β

Related Pathways

Neuronal Signaling

Field of Research

Neurological Disease

Purity

99.92

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

FC(F)(F)C1=CC=C(/C=C/B(O)O)C=C1

Molecular Formula

C9H8BF3O2

Molecular Weight

215.97

Precautions

H315, H319, H335

References & Citations

[1]Jiménez-Aligaga K, et al. Discovery of alkenylboronic acids as neuroprotective agents affecting multiple biological targets involved in Alzheimer's disease. Bioorg Med Chem Lett. 2013 Jan 15;23 (2) :426-9.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Related Products

Catalog	Name
HY-146005-01	Tau-aggregation and neuroinflammation-IN-1
HY-177854	Aβ aggregation-IN-4
HY-173282	Aβ aggregation-IN-2
HY-173621	Aβ1–42 aggregation inhibitor 3
HY-162093	Aβ1–42 aggregation inhibitor 2
HY-178927	Tau-aggregation-IN-4
HY-176060	Platelet aggregation-IN-3
HY-167743-01	Platelet aggregation-IN-2
HY-176936	Tau-aggregation-IN-5
HY-153430-01	Aβ/tau aggregation-IN-3

Alternative Products

Catalog	Name
T204182-01	Aβ aggregation-IN-1
T39781-01	Aβ/tau aggregation-IN-1
GTR19274266-01	SOD1-aggregation-IN-1
GTR19262698-01	Platelet aggregation-IN-1
T63481-01	Tau-aggregation-IN-1
T74811-01	Tau/Aβ40 aggregation-IN-1
MBS5800191-01	Abeta/tau aggregation-IN-1
MBS5820699	Tau protein aggregation-IN-1
GTR19185673-01	Tau-aggregation and neuroinflammation-IN-1
GTR19249982-01	α-syn aggregation inhibitor-1

Aβ aggregation-IN-1

Related Products

Alternative Products

Popular Products