Platelet aggregation-IN-3

CAT: 0931-MF-0114943-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0114943-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1029802-21-8
Target
Histamine Receptor|||5-HT Receptor|||Adrenergic Receptor
Related Pathways
Neuroscience|||GPCR/G Protein|||Immunology/Inflammation
Bioactivity
Platelet aggregation-IN-3 (Compound 5) acts as a ligand for H2 histamine receptors, ?2 (A, C) -adrenergic receptors (?2-AR), and 5-HT2 (B, C) serotonin receptors. This compound can inhibit platelet aggregation induced by ADP and collagen, and it also modulates tumor cell-induced platelet aggregation (TCIPA) . Platelet aggregation-IN-3 is a promising candidate for anti-platelet therapy in cardiovascular disease and the prevention of cancer-associated thrombosis and tumor metastasis.
Smiles
Cl.N1=C(NC2=CC=C3C(=C2)CCCC3)NCC1
Molecular Formula
C13H18ClN3
Molecular Weight
251.755
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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