tau/Aβ40 aggregation-IN-1

CAT:

804-HY-149272

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UNSPSC Description:
tau/Aβ40 aggregation-IN-1 (Compound 20) is a tau and Aβ40 aggregation inhibitor with IC50s of 1.8 μM and 1.3 μM, respectively[1].
Target Antigen:
Amyloid-β; Cholinesterase (ChE); Tau Protein
Type:
Reference compound
Related Pathways:
Neuronal Signaling
Applications:
Neuroscience-Neurodegeneration
Field of Research:
Neurological Disease
Assay Protocol:
https://www.medchemexpress.com/tau-aβ40-aggregation-in-1.html
Solubility:
10 mM in DMSO
Smiles:
COC1=CC=C2SC3=C(C(NCCC4CCN(CC4)C)=CC=C3C)C(C2=C1)=O
Molecular Weight:
396.55
References & Citations:
[1]Tonelli M, et al. Thioxanthenone-based derivatives as multitarget therapeutic leads for Alzheimer's disease. Eur J Med Chem. 2023 Mar 15;250:115169.
Shipping Conditions:
Room temperature
Clinical Information:
No Development Reported
CAS Number:
2973377-10-3

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