tau/Aβ40 aggregation-IN-1

tau/Aβ40 aggregation-IN-1

• CAS Number: 2973377-10-3
• UNSPSC Description: tau/Aβ40 aggregation-IN-1 (Compound 20) is a tau and Aβ40 aggregation inhibitor with IC50s of 1.8 μM and 1.3 μM, respectively[1].
• Target Antigen: Amyloid-β; Cholinesterase (ChE); Tau Protein
• Type: Reference compound
• Related Pathways: Neuronal Signaling
• Applications: Neuroscience-Neurodegeneration
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/tau-aβ40-aggregation-in-1.html
• Solubility: 10 mM in DMSO
• Smiles: COC1=CC=C2SC3=C(C(NCCC4CCN(CC4)C)=CC=C3C)C(C2=C1)=O
• Molecular Weight: 396.55
• References & Citations: [1]Tonelli M, et al. Thioxanthenone-based derivatives as multitarget therapeutic leads for Alzheimer's disease. Eur J Med Chem. 2023 Mar 15;250:115169.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported