Products for Research Use Only
RegisterLogin

Tau-aggregation-IN-1

CAT: 0804-HY-146135Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-146135Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Tau-aggregation-IN-1 (Compound D-519) is a tau441 protein aggregation inhibitor with an IC50 of 21 µM. Tau-aggregation-IN-1 is also a dopamine D2 and D3 receptor agonist[1].
CAS Number
1619269-19-0
UNSPSC
12352005
Target
Dopamine Receptor; Microtubule/Tubulin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton; GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/tau-aggregation-in-1.html
Solubility
10 mM in DMSO
Smiles
OC(C=C1C(C=C2)=CC=C2N(CC3)CCN3CCN([C@H]4CC5=C(N=C(S5)N)CC4)CCC)=C(C=C1)O
Molecular Formula
C28H37N5O2S
Molecular Weight
507.69
References & Citations
[1]Iva Ziu, et al. The multifunctional dopamine D2/D3 receptor agonists also possess inhibitory activity against the full-length tau441 protein aggregation. Bioorg Med Chem. 2020 Sep 15;28 (18) :115667.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
D2 Receptor; D3 Receptor

Related Products

CatalogName
HY-149272Tau/Aβ40 aggregation-IN-1
HY-153427Tau protein aggregation-IN-1
HY-146005-01Tau-aggregation and neuroinflammation-IN-1
HY-178927Tau-aggregation-IN-4
HY-176936Tau-aggregation-IN-5
HY-161448Tau-aggregation-IN-3
HY-153430-01Aβ/tau aggregation-IN-3
HY-W117986-01Aβ aggregation-IN-1
HY-13325Aβ aggregation modulator-1
HY-179533SOD1-aggregation-IN-1

Alternative Products

CatalogName
T39781-01Aβ/tau aggregation-IN-1
T63481-01Tau-aggregation-IN-1
T74811-01Tau/Aβ40 aggregation-IN-1
MBS5800191-01Abeta/tau aggregation-IN-1
MBS5820699Tau protein aggregation-IN-1
GTR19185673-01Tau-aggregation and neuroinflammation-IN-1
MBS5816748tau/Abeta40 aggregation-IN-1
GTR19219968Aβ/tau aggregation-IN-3
GTR19274888-01Aβ/tau aggregation-IN-4
GTR19234590-01Tau-aggregation-IN-3

Popular Products