FXIa-IN-15

CAT: 0931-T203612-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T203612-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

3053222-76-4

Target

Factor Xa

Related Pathways

Metabolism

Bioactivity

FXIa-IN-15 (Compound (S) -10h) is an inhibitor of factor XIa (FXIa) and plasma kallikrein (PKa) with IC50 values of 0.38 nM and 59.2 nM, respectively. It exhibits anticoagulant properties by prolonging the 50% activated partial thromboplastin time (aPTT) with an EC1.5X of 0.55 μM.

Smiles

O(C)C=1C(C2=C(C=CC(Cl)=C2)N3C=C(C(F)(F)F)N=N3)=CC(=O)N([C@@H](CC4=CC=CC=C4)C5=CN(N=N5)C6=CC=C(C(O)=O)C=C6)C1

Molecular Formula

C32H23ClF3N7O4

Molecular Weight

662.02

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Alternative Products

Catalog	Name
GTR19241033-01	FXIa-IN-15
HY-153817	FXIa-IN-13
HY-151196	FXIa-IN-10
HY-172400	FXIa-IN-16
MBS5805510	FXIa-IN-7
GTR19184454-01	FXIa-IN-8
GTR19274613-01	FXIa-IN-17
HY-150682	FXIa-IN-9
GTR19210246-01	FXIa-6f
HY-145349	FXIa-IN-6

FXIa-IN-15

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