Products for Research Use Only
RegisterLogin

JBJ-07-149

CAT: 0931-T203265-01Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T203265-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
2140807-58-3
Target
EGFR
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors, JAK/STAT signaling
Bioactivity
JBJ-07-149 is an inhibitor of EGFRL858R/T790M with an IC50 of 1.1 nM. It suppresses the proliferation of Ba/F3 cells with IC50 values of 4.9 μM when used alone, and 0.148 μM when combined with Cetuximab. Additionally, JBJ-07-149 can serve as a target protein ligand for synthesizing [DDC-01-163].
Smiles
O=C1C2=CC(=CC=C2CN1C(C(=O)NC3=NC=CS3)C=4C=CC=CC4)C=5C=NC(=CC5)N6CCNCC6
Molecular Formula
C28H26N6O2S
Molecular Weight
510.61
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Related Products

CatalogName
T63939-01JBJ-09-063
T72237-01JBJ-09-063 hydrochloride
T11713-01JBJ-02-112-05
T74561-01JBJ-09-063 TFA
T200308-01JBJ-08-178-01
T11714-01JBJ-04-125-02
T200874-01AV22-149
T200304-01XD2-149
T21421-01NCC-149
T39368-01GNE-149

Alternative Products

CatalogName
HY-151048-01JBJ-07-149
MBS5806604JBJ-09-063
M17084JBJ-16-111
HY-135805JBJ-04-125-02
HY-147183A-01JBJ-09-063 (TFA)
MBS5814691JBJ-09-063 hydrochloride
MBS5816507JBJ-09-063 TFA
MBS5797148JBJ-03-142-02
GTR19239056-01JBJ-08-178-01
HY-135914JBJ-02-112-05

Popular Products