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JBJ-08-178-01

CAT: 0931-T200308-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T200308-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2401867-58-9
Target
Others, Proteasome
Related Pathways
Ubiquitination, Others, Proteases/Proteasome
Bioactivity
JBJ-08-178-01, a mutant-selective tyrosine kinase inhibitor, targets (HER2) human epidermal growth factor receptor 2 and exhibits antitumoral activity. This compound not only diminishes HER2's kinase activity and protein levels through the induction of proteasomal degradation of the receptor but also shows promise in non-small-cell lung cancer research.
Smiles
N(C=1C2=C(C=C(OCC)C(NC(/C=C/CN(C)C)=O)=C2)N=CC1C#N)C3=CC(C)=C(OC4=CC=5N(C=C4)N=CN5)C=C3
Molecular Formula
C31H30N8O3
Molecular Weight
562.62
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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