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AChE/BChE-IN-25

CAT: 0931-T203222-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T203222-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Cholinesterase (ChE)
Related Pathways
Neuroscience
Bioactivity
AChE/BChE-IN-25 (Compound 6e) is an orally active inhibitor of hAChE and eqBChE, with IC50 values of 7.9 nM and 0.79 nM, respectively. This compound exhibits antioxidant activity, effective in scavenging free radicals with an IC50 of 22.91 μM. AChE/BChE-IN-25 demonstrates neuroprotective effects by reducing mitochondrial and cellular oxidative stress in a Drosophila Alzheimer's model and improves spatial and cognitive memory impairments induced by Scopolamine in mouse models.
Molecular Formula
C21H24ClN3O2
Molecular Weight
385.89
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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