DDC-01-163

• Target :

  PROTACs|||EGFR

• Related Pathways :

  Angiogenesis|||JAK/STAT signaling|||PROTAC|||Tyrosine Kinase/Adaptors

• Bioactivity :

  DDC-01-163 is a selective PROTAC degrader targeting EGFR mutants, with an IC50 of 45 nM.

• Smiles :

  O=C1NC(=O)C(N2C(=O)C=3C=CC=C(NCCOCCOCCOCCN4CCN(C=5N=CC(=CC5)C6=CC=C7C(=C6)C(=O)N(C7)C(C(=O)NC8=NC=CS8)C=9C=CC=CC9)CC4)C3C2=O)CC1

• Molecular Formula :

  C49H51N9O9S

• Molecular Weight :

  942.05

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2140806-84-2