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GPX4-IN-15

CAT: 0931-T201732-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T201732-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
3032966-42-7
Target
Cholinesterase (ChE), Glutathione Peroxidase
Related Pathways
Metabolism, Neuroscience
Bioactivity
GPX4-IN-15 (Compound C1) is an inhibitor of GPX4, demonstrating an inhibition rate of 19.8% at a concentration of 1 μM. This compound effectively inhibits the proliferation of cancer cell lines MDA-MB-468, BT-549, and MDA-MB-231, with IC50 values of 0.86 μM, 0.96 μM, and 0.48 μM respectively.
Smiles
O=C(OC)C1=CC=C(C=C1)N(C(=O)CCl)C2=CC=C(OC)C(Cl)=C2
Molecular Formula
C17H15Cl2NO4
Molecular Weight
368.21
Shipping Conditions
Ice Packs
Storage Temperature
-20°C