FXR/CES2 modulator 1

• Target :

  FXR

• Related Pathways :

  Metabolism

• Bioactivity :

  Compound LE-77, known as FXR/CES2 modulator 1, functions as a dual regulator that activates FXR and inhibits CES2. It effectively mitigates the intestinal toxicity of irinotecan.

• Smiles :

  O=C(O)COC=1C=CC(=CC1)C2=CC=C(OCC=3C(=NOC3C4CC4)C=5C(Cl)=CC=CC5Cl)C=C2

• Molecular Formula :

  C27H21Cl2NO5

• Molecular Weight :

  510.36

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  3004676-87-0