FXR/CES2 modulator 1

CAT: 0931-MF-0142686-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0142686-01Size:25 mg
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CAS Number
3004676-87-0
Target
FXR
Related Pathways
Metabolism
Bioactivity
Compound LE-77, known as FXR/CES2 modulator 1, functions as a dual regulator that activates FXR and inhibits CES2. It effectively mitigates the intestinal toxicity of irinotecan.
Smiles
O=C(O)COC=1C=CC(=CC1)C2=CC=C(OCC=3C(=NOC3C4CC4)C=5C(Cl)=CC=CC5Cl)C=C2
Molecular Formula
C27H21Cl2NO5
Molecular Weight
510.36
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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