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PROTAC SMARCA2 degrader-13

CAT: 0931-T200741-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T200741-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2568276-72-0
Target
PROTACs
Related Pathways
PROTAC
Bioactivity
SMARCA2 degrader-2 (compound I-322) is a PROTAC degrader targeting SMARCA2; it achieves a DC50 of less than 100 nM for the degradation of SMARCA2 protein in A549 cells, with a maximum degradation rate (Dmax%) exceeding 90% after 24 hours of treatment.
Smiles
O=C1NC(=O)C(N2C(=O)C=3C=CC=C(NC4CCC(N5CCC(N6N=CC(=C6)C=7C=C(N=NC7N)C=8C=CC=CC8O)CC5)CC4)C3C2=O)CC1
Molecular Formula
C37H39N9O5
Molecular Weight
689.76
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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