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HS-345

CAT: 0931-T200230-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-T200230-01Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1462329-41-4
Target
Akt|||Trk receptor
Related Pathways
Cytoskeletal Signaling|||PI3K/Akt/mTOR signaling|||Tyrosine Kinase/Adaptors
Bioactivity
HS-345, a TrkA/Akt inhibitor, exhibits potent anti-pancreatic cancer properties. This compound inhibits the growth and proliferation of pancreatic cancer cells by blocking the TrkA/Akt signaling pathway and induces cell apoptosis (Apoptosis) . Additionally, HS-345 inhibits angiogenesis by reducing the expression of HIF-1? and VEGF. It holds promise for use in pancreatic cancer research.
Smiles
O=S(=O)(C=1C=C(C=NC1N)C2=CN=C3NC=C(C=4C=CN=CC4)C3=C2)N(C)C
Molecular Formula
C19H18N6O2S
Molecular Weight
394.45
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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