ML-345

• Target:

  MMP

• Related Pathways:

  Proteases/Proteasome

• Bioactivity:

  ML-345 is a selective and potent IDE (insulin-degrading enzyme) inhibitor (IC50=188 nM) targeting the cysteine residue Cys819 in IDE, suitable for studying type 2 diabetes and Alzheimer's disease.

• Smiles:

  O=C1C2=CC(F)=CC=C2SN1C3=CC(=CC=C3N4CCOCC4)S(=O)(=O)N5CCOCC5

• Molecular Formula:

  C21H22FN3O5S2

• Molecular Weight:

  479.55

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1632125-79-1