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PROTAC YAP degrader-1

CAT: 0931-T200125-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T200125-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
YAP, PROTACs
Related Pathways
Stem Cells, PROTAC
Bioactivity
PROTAC YAP degrader-1, a targeted proteolysis promoting chimeric molecule, both degrades the YAP protein and inhibits its nuclear localization. This compound is formulated with Demethyl-NSC682769 as the target protein ligand, and utilizes (R, S, R) -AHPC-PEG2-C2-boc, which is the E3 ubiquitin ligase ligand + Linker conjugate. The linker incorporated in the design is Acid-PEG2-C2-Boc.
Molecular Formula
C56H62N6O9S
Molecular Weight
995.19
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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