N-Boc-cis-4-hydroxy-D-proline methylester

N-Boc-cis-4-hydroxy-D-proline methylester (CAS: 114676-69-6) is a high-purity chiral protected proline derivative and key pharmaceutical synthetic intermediate. The product has a stable cis-stereoconfiguration, with Boc amino protection group and methyl ester carboxyl protection group, retaining active hydroxyl functional groups. It features stable chiral configuration, excellent chemical selectivity and good solubility in organic solvents. The dual protection structure effectively avoids side reactions in the synthesis process, with high reaction controllability and low impurity generation rate. N-Boc-cis-4-hydroxy-D-proline methylester (CAS: 114676-69-6) has stable batch consistency and high chiral purity, widely used in chiral drug synthesis, peptide compound preparation and biomedical research.

Methyl (2R,4S) -1- (tert-butoxycarbonyl) -4-hydroxypyrrolidine-2-carboxylate, N-tert-Butoxycarbonyl-cis-4-hydroxy-D-proline methyl ester, Methyl N-Boc-cis-4-hydroxy-D-prolinate

1. Chiral Pharmaceutical Intermediate Synthesis: N-Boc-cis-4-hydroxy-D-proline methylester (CAS: 114676-69-6) is a core chiral building block for the synthesis of pyrrolidine-based small-molecule drugs. Its stable cis chiral structure and controllable active groups are widely applied in the R&D and industrial production of anti-viral, anti-inflammatory and central nervous system regulatory drugs. 2. Polypeptide Compound Preparation: N-Boc-cis-4-hydroxy-D-proline methylester (CAS: 114676-69-6) is used for the customized synthesis of functional polypeptide derivatives. The protected proline structure can be efficiently involved in peptide chain splicing reactions, helping to prepare high-purity bioactive peptides for biomedical and biochemical applications. 3. Chiral Material Derivatization: N-Boc-cis-4-hydroxy-D-proline methylester (CAS: 114676-69-6) supports diversified structural modification through active hydroxyl sites. It can be derivatized to prepare high-value chiral catalysts and chiral resolution reagents, which are applied in asymmetric synthesis and fine chiral chemical production. 4. Laboratory Chiral Chemistry Research: N-Boc-cis-4-hydroxy-D-proline methylester (CAS: 114676-69-6) serves as a standard high-purity chiral reagent for proline derivative research, providing stable raw material support for chiral synthetic process optimization and new drug molecule development.

98%

C11H19NO5

245.27

2 years under proper storage

White to Off-white Crystalline Solid

Research Grade, Pharmaceutical Intermediate Grade, Chiral Synthetic Grade

1.22±0.1 g/cm3