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N-Boc-propargylamine

CAT: 1139-92136-39-5-01Size: 10 gDry Ice: NoHazardous: No
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CAT#:1139-92136-39-5-01Size:10 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
N-Boc-propargylamine 92136-39-5 is a high-activity protected alkyne amine fine chemical intermediate. This compound is a tert-butoxycarbonyl (Boc) protected propargylamine derivative, containing both terminal alkyne active group and Boc-protected amino group. N-Boc-propargylamine 92136-39-5 features stable structure under neutral and alkaline conditions, while the Boc group can be selectively removed under acidic conditions to expose free amino groups. It has excellent chemical reactivity and orthogonality, widely used in click chemistry, pharmaceutical intermediate synthesis and polymer material modification fields.
Synonyms
Tert-Butyl propargylcarbamate, N- (tert-Butoxycarbonyl) propargylamine, Boc-propargylamine, tert-butyl N-prop-2-ynylcarbamate
HS Code
2924199090
Applications
1. Click Chemistry Synthetic Building Block: N-Boc-propargylamine 92136-39-5 is a core raw material for copper-catalyzed azide-alkyne cycloaddition click reactions. Its terminal alkyne structure enables efficient and specific coupling reactions, which is widely used in rapid molecular conjugation, biolabeling and high-purity compound synthesis. 2. Pharmaceutical Intermediate Synthesis: N-Boc-propargylamine 92136-39-5 serves as a key intermediate for the synthesis of anti-tumor, antiviral and targeted therapeutic drugs. The orthogonal protection and deprotection characteristics of its Boc-amine and alkyne groups support the precise construction of complex drug molecular frameworks and structural modification in pharmaceutical R&D. 3. Functional Polymer Material Modification: N-Boc-propargylamine 92136-39-5 is applied in the functional modification of polymer materials. It can be grafted onto polymer chains via alkyne click reaction to prepare functionalized polymers with active amino sites, which is widely used in the preparation of biomedical polymers and intelligent materials. 4. Biochemical and Laboratory Research: High-purity N-Boc-propargylamine 92136-39-5 is commonly used in life science research, biological probe preparation and organic synthesis mechanism verification. It provides reliable raw material support for scientific research institutions to carry out click chemistry experiments and new compound development.
Purity
≥98% (HPLC)
Molecular Formula
C8H13NO2
Molecular Weight
155.19
Shelf Life
2 years under proper storage
Appearance
White to off-white crystalline solid
Grade
Industrial Grade, Laboratory Grade
Density
1.018 g/cm3 (25°C)
Melting Point
40-44 °C