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Cis-4-Hydroxy-D-proline hydrochloride

CAT: 1139-77449-94-6-01Size: 10 gDry Ice: NoHazardous: No
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CAT#:1139-77449-94-6-01Size:10 g
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Description
Cis-4-Hydroxy-D-proline hydrochloride (CAS: 77449-94-6) is a high-purity chiral amino acid hydrochloride salt with stable cis stereoconfiguration, belonging to professional biochemical and pharmaceutical chiral intermediates. The product is a hydrochloride derivative of cis-4-hydroxy-D-proline, featuring excellent water solubility, stable chiral activity and high structural stability. Its protonated amino group structure effectively improves compound stability and solubility in aqueous and polar organic solvents, with low impurity content and stable batch consistency. cis-4-Hydroxy-D-proline hydrochloride (CAS: 77449-94-6) is widely used in chiral derivatization, pharmaceutical molecule synthesis and biochemical modification, serving as a core raw material for high-precision chiral synthesis and biomedical research.
Synonyms
(2R,4S) -4-Hydroxypyrrolidine-2-carboxylic acid hydrochloride, cis-4-Hydroxy-D-proline HCl, D-cis-4-Hydroxyproline hydrochloride, 4-cis-Hydroxy-D-proline hydrochloride
Applications
1. Chiral Pharmaceutical Intermediate Synthesis: cis-4-Hydroxy-D-proline hydrochloride (CAS: 77449-94-6) acts as a high-stability chiral building block for the synthesis of pyrrolidine-based pharmaceutical compounds. Its stable cis chiral configuration and activated functional groups support efficient structural modification and splicing, widely applied in the R&D and industrial production of antiviral, anti-inflammatory and central nervous system drug intermediates. 2. Bioactive Polypeptide Synthesis: cis-4-Hydroxy-D-proline hydrochloride (CAS: 77449-94-6) is used for the preparation of high-purity bioactive polypeptides. With superior water solubility and stable chiral activity, it can be efficiently involved in peptide chain synthesis reactions, optimizing the structural stability and biological activity of synthetic polypeptide products for biopharmaceutical applications. 3. Chiral Catalyst & Resolving Agent Preparation: cis-4-Hydroxy-D-proline hydrochloride (CAS: 77449-94-6) can be structurally modified through active hydroxyl and carboxyl groups to prepare high-efficiency chiral catalysts and chiral resolution reagents, which are widely used in asymmetric synthesis and fine chiral chemical industrial production. 4. Biochemical Laboratory Research: cis-4-Hydroxy-D-proline hydrochloride (CAS: 77449-94-6) serves as a standard high-purity biochemical reagent, applied in amino acid metabolism research, chiral stereochemistry experiments and new drug molecule screening in scientific research and industrial laboratories.
Purity
99%
Molecular Formula
C5H10ClNO3
Molecular Weight
167.59
Shelf Life
2 years under proper storage
Appearance
White Crystalline Solid
Grade
Biochemical Grade, Chiral Synthetic Grade, Pharmaceutical Intermediate Grade
Density
1.33±0.1 g/cm3
Melting Point
208-212 °C