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Cis-4-Hydroxy-D-proline

CAT: 1139-2584-71-6-01Size: 10 gDry Ice: NoHazardous: No
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CAT#:1139-2584-71-6-01Size:10 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cis-4-Hydroxy-D-proline (CAS: 2584-71-6) is a natural chiral hydroxyproline amino acid with stable cis stereoconfiguration, belonging to high-purity biochemical and pharmaceutical chiral intermediates. The product features a pyrrolidine ring structure with hydroxyl substitution at the 4-position, possessing excellent water solubility, stable chiral activity and high biological compatibility. It has strict stereochemical purity and low impurity content, with stable batch consistency. cis-4-Hydroxy-D-proline (CAS: 2584-71-6) can be used for chiral derivatization, polypeptide synthesis and biochemical modification, and is a core raw material for biomedical research and chiral pharmaceutical compound preparation.
Synonyms
4-cis-Hydroxy-D-proline, D-cis-4-Hydroxypyrrolidine-2-carboxylic acid, cis-4-Hydroxy-D-pyrrolidine-2-carboxylate, (2R,4S) -4-Hydroxypyrrolidine-2-carboxylic acid
Applications
1. Chiral Pharmaceutical Intermediate Synthesis: cis-4-Hydroxy-D-proline (CAS: 2584-71-6) serves as a critical chiral building block for the synthesis of pyrrolidine-based chiral drugs. Its stable cis chiral configuration and active hydroxyl and carboxyl groups support efficient structural modification, widely applied in the R&D and industrial production of antiviral, antibacterial and cardiovascular pharmaceutical intermediates. 2. Bioactive Polypeptide Preparation: cis-4-Hydroxy-D-proline (CAS: 2584-71-6) is commonly used for the synthesis of high-activity bioactive peptides. As a functional modified amino acid, it can be stably spliced into peptide chains to optimize the structural stability and biological activity of polypeptide products, applicable in biopharmaceutical and cosmetic raw material industries. 3. Chiral Catalyst Derivatization: cis-4-Hydroxy-D-proline (CAS: 2584-71-6) can be modified and derivatized through active functional groups to prepare high-efficiency chiral catalysts and chiral resolution reagents. It is widely used in asymmetric organic synthesis and fine chiral chemical production processes. 4. Biochemical Research & Experiment: cis-4-Hydroxy-D-proline (CAS: 2584-71-6) acts as a standard high-purity biochemical reagent, used for amino acid metabolism research, chiral stereochemistry experiments and biomedical mechanism exploration in laboratory and industrial research scenarios.
Purity
99%
Molecular Formula
C5H9NO3
Molecular Weight
131.13
Shelf Life
2 years under proper storage
Appearance
White Crystalline Powder
Grade
Biochemical Grade, Chiral Synthetic Grade, Pharmaceutical Intermediate Grade
Density
1.39±0.1 g/cm3
Melting Point
245-248 °C
EINECS
219-966-4