D-Prolinol

D-Prolinol (CAS 68832-13-3) is a high-purity chiral pyrrolidine alcohol compound with strict R-stereoconfiguration. Its molecular structure contains secondary amine and primary hydroxyl functional groups, featuring excellent chiral induction ability, good chemical reactivity and stable stereochemical properties. This product is soluble in water and conventional organic solvents, with low volatility and strong oxidation resistance under low-temperature sealed conditions. It is a classic and high-value chiral building block widely used in asymmetric catalytic synthesis, chiral ligand preparation and pharmaceutical intermediate development.

(R) - (-) -2-Pyrrolidinemethanol, (R) -2-Hydroxymethylpyrrolidine, D-2-Pyrrolidinemethanol, (2R) -Pyrrolidin-2-ylmethanol

2933990090

1. Asymmetric Catalysis & Chiral Ligand Synthesis: D-Prolinol (CAS 68832-13-3) is a core raw material for preparing proline-derived chiral ligands and organocatalysts. It can be modified to synthesize various high-efficiency chiral catalysts, which are widely used in asymmetric addition, cyclization and reduction reactions, effectively improving the stereoselectivity and enantiomeric excess rate of synthetic reactions. 2. Pharmaceutical Chiral Intermediate Preparation: This chiral amino alcohol is an important synthetic intermediate for high-purity chiral drugs. D-Prolinol (CAS 68832-13-3) is commonly used in the R&D and production of central nervous system drugs, anti-tumor drugs and cardiovascular chiral medicines, providing accurate chiral skeleton support for drug molecular design and optimizing pharmacological activity and safety. 3. Fine Chemical Chiral Derivatization: D-Prolinol (CAS 68832-13-3) has dual active functional groups of amine and hydroxyl, which can participate in esterification, amidation and substitution reactions. It is widely used for structural modification and chiral resolution of high-value fine chemicals, helping to prepare high-purity single-enantiomer compounds. 4. Laboratory R&D and Pilot Production: As a standard high-stability chiral pyrrolidine reagent, D-Prolinol (CAS 68832-13-3) is extensively used in laboratory asymmetric synthesis research, new chiral compound development and process optimization, providing stable and high-purity raw material support for chemical scientific research and pilot-scale industrial production.

≥99% (GC)

C5H11NO

101.15

2 years under proper storage

Colorless to pale yellow transparent liquid

Fine chemical grade, Chiral reagent grade, Pharmaceutical intermediate grade

1.036±0.01 g/cm3 (20 °C, lit.)

0 °C

75 °C (2 mmHg)