N-Boc-D-prolinol

CAT: 0804-HY-78924Size: 25 gDry Ice: NoHazardous: No

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CAT#:0804-HY-78924Size:25 g

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Description

N-Boc-D-prolinol is a protected chiral proline derivative. N-Boc-D-prolinol facilitates the synthesis of highly selective histamine H1 and H3 receptor antagonists. N-Boc-D-prolinol can be used in the research of allergic rhinitis[1][2].

CAS Number

83435-58-9

UNSPSC

12352200

Hazard Statement

H302, H315, H319, H335

Target

Amino Acid Derivatives; Biochemical Assay Reagents

Type

Biochemical Assay Reagents

Related Pathways

Others

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/n-boc-d-prolinol.html

Purity

99.99

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(N1[C@H](CCC1)CO)OC(C)(C)C

Molecular Formula

C10H19NO3

Molecular Weight

201.27

Precautions

H302, H315, H319, H335

References & Citations

[1]Procopiou PA, et al. The discovery of phthalazinone-based human H1 and H3 single-ligand antagonists suitable for intranasal administration for the treatment of allergic rhinitis. J Med Chem. 2011 Apr 14;54 (7) :2183-95. |[2]Procopiou PA, et al. Synthesis and pharmacological investigation of azaphthalazinone human histamine H (1) receptor antagonists. Bioorg Med Chem. 2012 Oct 15;20 (20) :6097-108.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Biochemical Assay Reagents

Clinical Information

No Development Reported

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