SAP49 Antibody

CAT: 0498-bsm-70253MSize: 100 µLDry Ice: NoHazardous: No
CAT#:0498-bsm-70253MSize:100 µL
Selected
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
The spliceosome associated protein of ~49 kDa (SAP49), also known as SF3B4, is a widely expressed nuclear splicing factor that has been shown to have RNA binding activity as well as direct interaction with SAP145 (Champion-Arnaud and Reed 1994) . The SAP145-SAP49 complex has recently been implicated in cell cycle progression as Vpr (viral protein 1 of HIV-1) has been shown to bind SAP145 thus interfering with the proper formation and functioning of the SAP145-SAP49 complex (Terada and Yasuda 2006) .
Synonyms
AFD1 antibody, Hsh49 antibody, MGC10828 antibody, Pre mRNA splicing factor SF3b 49 kDa subunit antibody, Pre-mRNA-splicing factor SF3b 49 kDa subunit antibody, SAP 49 antibody, SAP49 antibody, Sf3b4 antibody, SF3B4 antibody, SF3B4_HUMAN antibody, SF3b49 antibody, SF3b50 antibody, Spliceosomal protein antibody, Spliceosome associated protein (U2 snRNP) antibody, Spliceosome associated protein 49 antibody, Spliceosome-associated protein 49 antibody, Splicing factor 3b subunit 4 49kDa antibody, Splicing factor 3B subunit 4 antibody
Gene ID
10262
Swiss Prot
Q15427
Host
Mouse
Cross Reactivity
Human, Mouse, Rat
Target
SAP49
Clonality
Monoclonal
Isotype
IgG2b
Clone
3A1
Conjugation
Unconjugated
Source
Recombinant full length human SAP49 expressed in and purified from E. Coli.
Applications
WB, IHC
Purification
Purified by Protein G.
Concentration
Lot Dependent
Dilution
WB (1:300-5000), IHC ()
Buffer
PBS + 50% glycerol and 5 mm NaN3
Modification
Unmodified
Storage Conditions
Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.
Specificity
Specific for endogenous levels of the ~49 kDa SAP49 protein.
Gene ID URL
10262

Popular Products