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SAP49 polyclonal antibody

CAT: 0384-BS62486-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS62486-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
SF3B4 is part of the SF3b complex which associates with the U2 snRNP component of the spliceosome and is essential for spliceosome assembly. SF3B4 can associate with BMPR-1A to inhibit BMP-mediated cell differentiation. Haploinsufficiency of SF3B4 has been described in Nager syndrome, a disease of craniofacial malformation condition. Increased copy number of SF3B4 has been shown to play a role in hepatocellular carcinoma progression.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Splicing factor 3B subunit 4; Pre-mRNA-splicing factor SF3b 49 kDa subunit; Spliceosome-associated protein 49; SAP 49; SF3B4; SAP49
Swiss Prot
Q15427
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to Human SAP49.
Conjugation
Unconjugated
Applications
WB IHC
Dilution
WB:1:500~1:1000 IHC:1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 49 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
SAP49 polyclonal antibody detects endogenous levels of SAP49 protein.
Applications Notes
Western blot (WB) analysis of SAP49 polyclonal antibody at 1:500 dilution LaneA:L02 whole cell lysate LaneB:A549 whole cell lysate LaneC:HEK293T whole cell lysate LaneD:CT26 whole cell lysate LaneE:PC12 whole cell lysate
Host or Source
Rabbit

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