GluR1 Antibody

• Background :

  The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by α-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR) . The AMPAR are comprised of four distinct glutamate receptor subunits designated (GluR1-4) and they play key roles in virtually all excitatory neurotransmission in the brain (Keinänen et al., 1990; Hollmann and Heinemann, 1994) .

• Synonyms :

  GLUR 1 antibody, GLUR A antibody, AMPA 1 antibody, AMPA selective glutamate receptor 1 antibody, AMPA-selective glutamate receptor 1 antibody, GluA1 antibody, GLUH1 antibody, GluR K1 antibody, GluR-1 antibody, GluR-A antibody, GluR-K1 antibody, GLUR1 antibody, GLURA antibody, GluRK1 antibody, Glutamate receptor 1 antibody, Glutamate receptor ionotropic AMPA 1 antibody, Glutamate receptor ionotropic antibody, Glutamate receptor, ionotropic, AMPA 1 antibody, Gria1 antibody, GRIA1_HUMAN antibody, HBGR1 antibody, MGC133252 antibody, OTTHUMP00000160643 antibody, OTTHUMP00000165781 antibody, THUMP00000224241 antibody, OTTHUMP00000224242 antibody, OTTHUMP00000224243 antibody

• Gene ID :

  50592

• Swiss Prot :

  P19490

• Host :

  Mouse

• Cross Reactivity :

  Mouse, Rat

• Target :

  GluR1

• Clonality :

  Monoclonal

• Isotype :

  IgG2a

• Clone :

  RH95

• Conjugation :

  Unconjugated

• Source :

  Synthetic peptide corresponding to amino acid residues from the N-terminal region of rat GluR1, conjugated to keyhole limpet hemocyanin (KLH) .

• Applications :

  WB

• Purification :

  Purified by Protein G.

• Concentration :

  Lot Dependent

• Dilution :

  WB (1:300-5000)

• Buffer :

  10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.

• Modification :

  Unmodified

• Storage Conditions :

  Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

• Specificity :

  Specific for endogenous levels of the ~105 kDa GluR1 protein.

• Gene ID URL :

  50592