Products for Research Use Only

Autogramin-2

CAT: 0498-bs-82865C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82865C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Autogramin-2 is an inhibitor of autophagy (autophagy induced by amino acid starvation IC50 = 270 nM; Rapamycin IC50 = 140 nM) acting via selective targeting of the cholesterol transfer protein GRAM domain-containing protein 1A (GRAMD1A) . Autogramin-2 inhibition of GRAMD1A inhibits biogenesis of the autophagosome.
Conjugation
Unconjugated
Buffer
Off-white solid
Storage Conditions
-20°C