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FB23-2

CAT: 0498-bs-83809C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-83809C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
FB23-2 is an inhibitor (IC50 = 2.6 µM) of the mRNA m6A demethylase fat-mass- and obesity-associated protein (FTO) .1 Displays significant anti-proliferative activity in NB4 (IC50 = 0.8 µM) and MONOMAC6 (IC50 = 1.5 µM) cells. Selective against the RNA demethylase ALKB5. FB23-2 induced myeloid differentiation and apoptosis in acute myeloid leukemia cells. FB23-2 suppressed the proliferation and migration of hepatocellular carcinoma cells via suppressing the expression of the kinase ERBB3 and human tubulin beta class Iva (TUBB4A) .2
Conjugation
Unconjugated
Buffer
Off-white solid
Storage Conditions
-20°C

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Alternative Products

CatalogName
408023FB23-2

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