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2-APB

CAT: 0498-bs-82136C-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82136C-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
An IP3 receptor antagonist (IC50=42 μM) .1 Inhibits store-operated Ca2+ channels at high concentrations (50 μM) but stimulates at low concs. (<10 μM) .2 Modulates TRP channels, blocking TRPC1, TRPC3, TRPC5, TRPC6, TRPV6, TRPM3, TRPM7, TRPM8, TRPP2 and at higher concentrations, activating TRPV1, TRPV2, TRPV3.3,4 Also inhibits selected GAP junction subtypes.5
Conjugation
Unconjugated
Buffer
White solid
Storage Conditions
-20°C

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