Ponatinib Hydrochloride

• Description:

  Ponatinib Hydrochloride (AP-24534 Hydrochloride) is a hydrochloride of ponatinib. Ponatinib is an orally active multi-targeted kinase inhibitor with IC50s of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM, and 5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectively.

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  569.02

• Molecular Formula:

  C29H28ClF3N6O

• Notes:

  Research use only, not for human use.

• Receptor:

  Src | PDGFR | VEGFR | FGFR

• CAS Number:

  1114544-31-8