Poziotinib hydrochloride

• Description:

  Poziotinib hydrochloride irreversibly inhibits EGFR (HER1 or ErbB1), including EGFR mutants, HER2, and HER4, thereby inhibiting the proliferation of tumor cells that overexpress these receptors. It is an orally bioavailable, quinazoline-based pan epidermal growth factor receptor (EGFR or HER) inhibitor with potential antineoplastic activity.

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  527.8

• Molecular Formula:

  C23H22Cl3FN4O3

• Notes:

  Research use only, not for human use.

• Receptor:

  EGFR

• CAS Number:

  1429757-68-5