Ponatinib

• Target :

  PDGFR|||c-Kit|||Autophagy|||FGFR|||VEGFR|||Bcr-Abl|||Src

• Related Pathways :

  Cytoskeletal Signaling|||Autophagy|||Angiogenesis|||Tyrosine Kinase/Adaptors

• Purity :

  0.9974

• Bioactivity :

  Ponatinib (AP24534) is an orally available, multitargeted kinase inhibitor with IC50 values of 0.37 nM (Abl), 1.1 nM (PDGFR?), 1.5 nM (VEGFR2), 2.2 nM (FGFR1), and 5.4 nM (Src) .

• Smiles :

  C(#CC1=CC(C(NC2=CC(C(F)(F)F)=C(CN3CCN(C)CC3)C=C2)=O)=CC=C1C)C=4N5C(=NC4)C=CC=N5

• Molecular Formula :

  C29H27F3N6O

• Molecular Weight :

  532.56

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  943319-70-8