Ponatinib

• Description :

  Ponatinib (AP 24534) is a potent, orally active pan-inhibitor of BCR-ABL kinase with IC50 of 0.37 and 2.0 nM for ABL and mutant ABLT315I, respectively.

• Stability :

  ≥ 2 years

• Purity :

  >98% (HPLC)

• Weight :

  532.5595

• Molecular Formula :

  C29H27F3N6O

• Notes :

  Research use only, not for human use.

• Receptor :

  Abl|c-Kit|c-Src|FGFR1|PDGFRα|VEGFR2|LYN

• CAS Number :

  943319-70-8