Ponatinib

• Description:

  Ponatinib (AP 24534) is a potent, orally active pan-inhibitor of BCR-ABL kinase with IC50 of 0.37 and 2.0 nM for ABL and mutant ABLT315I, respectively.

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  532.5595

• Molecular Formula:

  C29H27F3N6O

• Notes:

  Research use only, not for human use.

• Receptor:

  Abl|c-Kit|c-Src|FGFR1|PDGFRα|VEGFR2|LYN

• CAS Number:

  943319-70-8