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Trilaciclib hydrochloride

CAT: 1410-M22845-01Size: 1 EachDry Ice: NoHazardous: No
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CAT#:1410-M22845-01Size:1 Each
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Description
Trilaciclib hydrochloride is an inhibitor of CDK4/6 (IC50s: 1 nM and 4 nM for CDK4 and CDK6) .Incubation with Trilaciclib hydrochloride (G1T28) for 24 hours can induce a strong G1 cell cycle arrest (time=0) . Cells have re-entered the cell cycle and demonstrate cell-cycle kinetics similar to untreated control cells By 16 hours after Trilaciclib hydrochloride washout.
CAS Number
1977495-97-8
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
519.47
Molecular Formula
C24H32Cl2N8O
Notes
Research use only, not for human use.
Receptor
Cdk4/cyclin D1|cdk6/cyclin D3