Products for Research Use Only

APC Rabbit mAb

CAT: 0866-RDSA66852Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0866-RDSA66852Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Tumor suppressor. Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator. APC activity is correlated with its phosphorylation state. Activates the GEF activity of SPATA13 and ARHGEF4. Plays a role in hepatocyte growth factor (HGF) -induced cell migration. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex.
Description
This is a APC Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
APC; APC protein; Adenomatous polyposis coli protein; DP2.5; mAPC
Swiss Prot
P25054
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human APC
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Recombinant Antibody
Applications
WB, IHC, ICC/IF, IP
Purification Method
Affinity purification
Assay Type
Antibody
Dilution
WB 1:500-1:2000, IHC 1:50-1:200, ICC/IF 1:50-1:200, IP 1:50, FC 1:50
Buffer
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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