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BD-3

CAT: 0209-M10-023-L1000Size: 1000 µgDry Ice: NoHazardous: No
CAT#:0209-M10-023-L1000Size:1000 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The α-defensins are distinguished from the β-defensins by the pairing of their three disulfide bonds. To date, six human β-defensins have been identified; BD-1, BD-2, BD-3, BD-4, BD-5 and BD-6. β-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they can act as chemoattractants towards immature dendritic cells and memory T cells. The β-defensin proteins are expressed as the C-terminal portion of precursors, and are released by proteolytic cleavage of a signal sequence and, in some cases, a propeptide sequence. β-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. Recombinant Murine BD-3 is a 4.6 kDa protein containing 41 amino acid residues.
Synonyms
Beta-Defensin 3, DEFB3, DEFB103A
NCBI Gene ID
27358
UniProt
Q9WTL0
Accession Number
NP_038784.1
Accession Number mRNA
NM_013756.2
Reactivity
Mouse
Cross Reactivity
Mouse
Sequence
KKINNPVSCL RKGGRCWNRC IGNTRQIGSC GVPFLKCCKR K
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
≥ 98% by SDS-PAGE gel and HPLC analyses
Bioactivity
Not available.
Length
41
Form
Lyophilized
Molecular Weight
4.6 kDa
Host or Source
E. coli

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Alternative Products

CatalogName
ant-050BD 3
301317BD3 (Beta-Defensin 3, BD-3, BD 3)
301317-APCBD3 (Beta-Defensin 3, BD-3, BD 3) (APC)
MBS6451984-01BD3 (Beta-Defensin 3, BD-3, BD 3) (Biotin)
301317-FITCBD3 (Beta-Defensin 3, BD-3, BD 3) (FITC)
MBS6451985-01BD3 (Beta-Defensin 3, BD-3, BD 3) (FITC)
MBS6451986-01BD3 (Beta-Defensin 3, BD-3, BD 3) (HRP)
301317-PEBD3 (Beta-Defensin 3, BD-3, BD 3) (PE)
301317-BiotinBD3 (Beta-Defensin 3, BD-3, BD 3) (Biotin)
MBS6451982-01BD3 (Beta-Defensin 3, BD-3, BD 3) (AP)

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