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R113A rabbit pAb

CAT: 0855-ES18901-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES18901-01Size:50 µL
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UniProt
O15541
Swiss Prot
O15541
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from human R113A AA range: 76-126
Clonality
Polyclonal
Source
Rabbit
Applications
WB
Concentration
1 mg/ml
Dilution
WB 1:1000-2000
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Nucleus . Nucleus speckle . Colocalizes with ASCC2 in nuclear foci after DNA damage by alkylating agents. In the absence of DNA damage, colocalizes with the spliceosome components SNRNP200/BRR2 and PRPF8 in nuclear speckles. .
Gene ID (Human)
7737

UniProtKB · O15541

E3 ubiquitin-protein ligase RNF113A

R113A_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O15541
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
RNF113A
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.3.2.27
Processing
—
Secondary accessions
B2RBR7
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationMethylationPhosphoprotein

Biological process

DNA damageDNA repairmRNA processingmRNA splicingUbl conjugation pathway

Ligand

Metal-bindingZinc

Cellular component

NucleusSpliceosome

Molecular function

Transferase

Domain

Zinc-finger