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CD160 Antibody

CAT: 0223-7475-01Size: 0.02 mgDry Ice: NoHazardous: No
CAT#: 7475-01Size: 0.02 mg
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PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CD160, also known as BY55, is a lipid-anchored cell membrane glycoprotein that contains one immunoglobulin-like domain (1) . It is expressed in small intestine, spleen and functional NK and T cytotoxic lymphocytes (1,2) . CD160 exists as a disulfide-linked homomultimer that functions as a receptor for MHC (major histocompatability complex) molecules and is thought to regulate the function of NK cells (2,3) . Additionally, CD160 interacts with TNFRSF14 and, via this interaction, is able to negatively regulate CD4+ T cell activation, indicating a role in immune system regulation (4) .
NCBI Gene ID
11126
Swiss Prot
O95971
Accession Number
NP_008984
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Purification
CD160 Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1204 - K562 Cell Lysate
Concentration
1 mg/mL
Buffer
CD160 Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
CD160 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.
Fragment
IgG
Specificity
CD160 antibody is human and mouse reactive. Multiple isoforms of CD160 are known to exist.
Symbol
CD160
NCBI Official Name
CD160 molecule
NCBI Organism
Homo sapiens
Background Reference 01
Anumanthan A, Bensussan A, Boumsell L, et al. Cloning of BY55, a novel Ig superfamily member expressed on NK cells, CTL, and intestinal intraepithelial lymphocytes. J. Immunol. 1998; 161:2780-90.
Background Reference 02
Agrawal S, Marquet J, Freeman GJ, et al. Cutting edge: MHC class I triggering by a novel cell surface ligand costimulates proliferation of activated human T cells. J. Immunol. 1999; 162:1223-6.
Background Reference 03
Le Bouteiller P, Tabiasco J, Polgar B, et al. CD160: a unique activating NK cell receptor. Immunol. Lett. 2011;138:93-6
Background Reference 04
Chabot S, Jabrane-Ferrat N, Bigot K, et al. A novel antiangiogenic and vascular normalization therapy targeted against human CD160 receptor. J. Exp. Med. 2011; 208:973-86.
Other Product Names
CD160 Antibody : NK1, BY55, NK28, CD160 antigen, Natural killer cell receptor BY55
Tested Applications
ELISA, WB, IF
Protein ID
5901910
Physical Properties
Liquid

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