Tyrosine Hydroxylase (phospho Ser31) Antibody

• Background:

  Plays an important role in the physiology of adrenergic neurons.

• NCBI Gene ID:

  7054

• Swiss Prot:

  P07101

• Accession Number:

  NP_000351.2

• Host:

  Rabbit

• Reactivity:

  Human, Rat

• Immunogen:

  Tyrosine Hydroxylase (Phospho-Ser31) antibody was raised against a peptide sequence around phosphorylation site of serine31 (V-T-S (p) -P-R) derived from human Tyrosine Hydroxylase.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Phospho-Specific, Neuroscience

• Purification:

  Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

• Concentration:

  1 mg/mL

• Buffer:

  Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Modification:

  Phospho-Specific

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store antibody at -20˚ C for up to one year.

• Calculated Molecular Weight:

  55 - 60 kDa

• Specificity:

  This antibody detects endogenous levels of Tyrosine Hydroxylase only when phosphorylated at serine 31.

• Applications Notes:

  Western Blot: 1:500~1:1000

• Symbol:

  TH

• NCBI Official Name:

  Tyrosine hydroxylase

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Vazin T, et al. Stem Cells. 2008 Jun;26 (6) : 1517-25Pistocchi A, et al. BMC Dev Biol. 2008 Mar 10;8:27 Fukakusa A, et al. J Pharmacol Sci. 2008 Feb;106 (2) : 321-4.

• Other Product Names:

  TYH, DYT14, DYT5b, Tyrosine 3-hydroxylase, TH, Tyrosine 3-monooxygenase

• Tested Applications:

  WB

• Protein ID:

  88900503

• Physical Properties:

  Liquid