SPRR1A Antibody

• Background:

  Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane.

• NCBI Gene ID:

  6698

• Swiss Prot:

  P35321

• Accession Number:

  P35321

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This SPRR1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 61-89 amino acids from the C-terminal region of human SPRR1A.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  10 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  SPRR1A

• NCBI Official Name:

  Cornifin-A

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Jarzab, J., et al. Int. Arch. Allergy Immunol. 151 (1) :28-37 (2010)

• Background Reference 02:

  Stemmler, S., et al. Int. J. Immunogenet. 36 (4) :217-222 (2009)

• Background Reference 03:

  Kainu, K., et al. Exp. Dermatol. 18 (2) :109-115 (2009)

• Background Reference 04:

  Bonilla, I.E., et al. J. Neurosci. 22 (4) :1303-1315 (2002)

• Other Product Names:

  Cornifin-A, 19 kDa pancornulin, SPRK, Small proline-rich protein IA, SPR-IA, SPRR1A

• Tested Applications:

  WB

• Protein ID:

  215273890

• Physical Properties:

  Liquid