SPRR2A Antibody

• Background :

  Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane.

• NCBI Gene ID :

  6700

• Swiss Prot :

  P35326

• Accession Number :

  P35326

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This SPRR2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 48-72 amino acids from the C-terminal region of human SPRR2A.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cell Cycle, Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  8 kDa

• Fragment :

  Rabbit IgG

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  SPRR2A

• NCBI Official Name :

  Small proline-rich protein 2A

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Kainu, K., et al. Exp. Dermatol. 18 (2) :109-115 (2009)

• Background Reference 02 :

  Demetris, A.J., et al. J. Hepatol. 48 (2) :276-288 (2008)

• Background Reference 03 :

  Tong, L., et al. Invest. Ophthalmol. Vis. Sci. 47 (5) :1938-1946 (2006)

• Background Reference 04 :

  Hong, S.H., et al. Mol. Cells 17 (3) :477-484 (2004)

• Other Product Names :

  Small proline-rich protein 2A, SPR-2A, 2-1, SPRR2A

• Tested Applications :

  WB

• Physical Properties :

  Liquid