SPRR1B Antibody

• Background:

  SPRR1B is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. Can function as both amine donor and acceptor in transglutaminase-mediated cross-linkage.

• NCBI Gene ID:

  6699

• Swiss Prot:

  P22528

• Accession Number:

  P22528

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This SPRR1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-89 amino acids from the C-terminal region of human SPRR1B.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  10 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  SPRR1B

• NCBI Official Name:

  Cornifin-B

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Stemmler, S., et.al., Int. J. Immunogenet. 36 (4), 217-222 (2009)

• Background Reference 02:

  Kainu, K., et.al., Exp. Dermatol. 18 (2), 109-115 (2009)

• Other Product Names:

  Cornifin-B, 149 kDa pancornulin, Small proline-rich protein IB, SPR-IB, SPRR1B

• Tested Applications:

  WB, IHC-P

• Protein ID:

  84028265

• Physical Properties:

  Liquid