GRB2 Antibody

CAT: 0223-62-216Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-62-216Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
GRB2 binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway.
NCBI Gene ID
2885
Swiss Prot
P62993
Accession Number
P62993
Host
Rabbit
Reactivity
Human
Immunogen
This GRB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-216 amino acids from human GRB2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Xenopus, Chicken, Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
25 kDa
Fragment
Rabbit Ig
Symbol
GRB2
NCBI Official Name
Growth factor receptor-bound protein 2
NCBI Organism
Homo sapiens
Background Reference 01
Kondo, A., J. Biol. Chem. 283 (3), 1428-1436 (2008) Morimatsu, M., Proc. Natl. Acad. Sci. U.S.A. 104 (46), 18013-18018 (2007) Martinez, N., Cell. Signal. 19 (11), 2277-2285 (2007)
Other Product Names
Growth factor receptor-bound protein 2, Adapter protein GRB2, Protein Ash, SH2/SH3 adapter GRB2, GRB2, ASH
Tested Applications
WB, IHC-P
Protein ID
51702266
Physical Properties
Liquid

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