CTSD Antibody

• Background:

  CTSD encodes a lysosomal aspartyl protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. This proteinase, which is a member of the peptidase C1 family, has a specificity similar to but narrower than that of pepsin A. Transcription of this gene is initiated from several sites, including one which is a start site for an estrogen-regulated transcript.

• NCBI Gene ID:

  1509

• Swiss Prot:

  P07339

• Accession Number:

  P07339

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This CTSD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 377-408 amino acids from the C-terminal region of human CTSD.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle, Neuroscience, Signal Transduction

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  45 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  CTSD

• NCBI Official Name:

  Cathepsin D

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Christensen, B., et al. J. Biol. Chem. 285 (11) :7929-7937 (2010)

• Background Reference 02:

  Albayrak, O., et al. J. Gerontol.Biol. Sci. Med. Sci. 65 (3) :219-224 (2010)

• Background Reference 03:

  Heinrich, M., et al. EMBO J. 18 (19) :5252-5263 (1999)

• Other Product Names:

  Cathepsin D, Cathepsin D light chain, Cathepsin D heavy chain, CTSD, CPSD

• Tested Applications:

  WB

• Protein ID:

  115717

• Physical Properties:

  Liquid