CTSE Antibody

• Background:

  CTSE is a gastric aspartyl protease that functions as a disulfide-linked homodimer. This protease, which is a member of the peptidase C1 family, has a specificity similar to that of pepsin A and cathepsin D. It is an intracellular proteinase that does not appear to be involved in the digestion of dietary protein and is found in highest concentration in the surface of epithelial mucus-producing cells of the stomach. It is the first aspartic proteinase expressed in the fetal stomach and is found in more than half of gastric cancers. It appears, therefore, to be an oncofetal antigen.

• NCBI Gene ID:

  1510

• Swiss Prot:

  P14091

• Accession Number:

  P14091

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This CTSE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 157-187 amino acids from the Central region of human CTSE.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Immunology

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  43 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  CTSE

• NCBI Official Name:

  Cathepsin E

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Caruso, M., Virchows Arch. 454 (3), 291-302 (2009)

• Background Reference 02:

  Burster, T., Biochem. Biophys. Res. Commun. 377 (4), 1299-1303 (2008)

• Other Product Names:

  Cathepsin E, Cathepsin E form I, Cathepsin E form II, CTSE

• Tested Applications:

  WB, IHC-P, Flow

• Protein ID:

  46397366

• Physical Properties:

  Liquid