CTSA Antibody

• Background :

  CTSA encodes a glycoprotein which associates with lysosomal enzymes beta-galactosidase and neuraminidase to form a complex of high molecular weight multimers. The formation of this complex provides a protective role for stability and activity. Deficiencies in this gene are linked to multiple forms of galactosialidosis.

• NCBI Gene ID :

  5476

• Swiss Prot :

  P10619

• Accession Number :

  P10619

• Host :

  Rabbit

• Reactivity :

  Human, Mouse

• Immunogen :

  This CTSA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-45 amino acids from the N-terminal region of human CTSA.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Obesity, Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  54 kDa

• Fragment :

  Rabbit Ig

• Symbol :

  CTSA

• NCBI Official Name :

  Lysosomal protective protein

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Reich, M., et al. Immunol. Lett. 128 (2) :143-147 (2010)

• Background Reference 02 :

  Bonten, E.J., et al. J. Biol. Chem. 284 (41) :28430-28441 (2009)

• Background Reference 03 :

  Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :

• Background Reference 04 :

  Tatano, Y., et al. J. Med. Invest. 53 (1-2), 103-112 (2006) :

• Other Product Names :

  Lysosomal protective protein, Carboxypeptidase C, Carboxypeptidase L, Cathepsin A, Protective protein cathepsin A, PPCA, Protective protein for beta-galactosidase, Lysosomal protective protein 32 kDa chain, Lysosomal protective protein 20 kDa chain, CTSA, PPGB

• Tested Applications :

  WB, IHC-P

• Protein ID :

  20178316

• Physical Properties :

  Liquid