CTSK Antibody

• Background:

  The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature.

• NCBI Gene ID:

  1513

• Swiss Prot:

  P43235

• Host:

  Rabbit

• Reactivity:

  Mouse, Rat, Duck

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 115-329 of human CTSK (NP_000387.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle, Neuroscience, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  Mouse liver

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 41kDa

• Fragment:

  IgG

• Symbol:

  CTSK

• NCBI Official Name:

  Cathepsin K

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  CTSK, cathepsin K, CTS02, CTSO, CTSO1, CTSO2, MGC23107, PKND, PYCD, cathepsin K (pycnodysostosis), cathepsin O1, cathepsin O2, cathepsin X

• Tested Applications:

  WB, IHC

• Physical Properties:

  Liquid