ITPKC Antibody

• Background :

  ITPKC encodes a member of the inositol 1,4,5-trisphosphate [Ins (1,4,5) P (3) ] 3-kinase family of enzymes that catalyze the phosphorylation of inositol 1,4,5-trisphosphate to 1,3,4,5-tetrakisphosphate. The encoded protein is localized to the nucleus and cytoplasm and has both nuclear import and nuclear export activity. Single nucleotide polymorphisms in this gene are associated with Kawasaki disease.

• NCBI Gene ID :

  80271

• Swiss Prot :

  Q96DU7

• Accession Number :

  Q96DU7

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This ITPKC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 89-117 amino acids from the N-terminal region of human ITPKC.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  75 kDa

• Fragment :

  Rabbit Ig

• Symbol :

  ITPKC

• NCBI Official Name :

  Inositol-trisphosphate 3-kinase C

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Chi, H. Hum. Mol. Genet. 19 (6), 1147-1151 (2010)

• Background Reference 02 :

  Onouchi, Y. Nat. Genet. 40 (1), 35-42 (2008)

• Background Reference 03 :

  Nalaskowski, M.M. Biol. Chem. 387 (5), 583-593 (2006)

• Other Product Names :

  Inositol-trisphosphate 3-kinase C, Inositol 1,5-trisphosphate 3-kinase C, IP3 3-kinase C, IP3K C, InsP 3-kinase C, ITPKC, IP3KC

• Tested Applications :

  WB, IHC-P, Flow

• Physical Properties :

  Liquid