ITPKB Antibody

• Background :

  ITPKB regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins (1,3,4,5) P4. The activity of this encoded protein is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity.

• NCBI Gene ID :

  3707

• Swiss Prot :

  P27987

• Accession Number :

  P27987

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This ITPKB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 23-54 amino acids from the N-terminal region of human ITPKB.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Signal Transduction

• Purification :

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  102 kDa

• Fragment :

  Rabbit Ig

• Symbol :

  ITPKB

• NCBI Official Name :

  Inositol-trisphosphate 3-kinase B

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Dewaste, V., et al., Biochem. Biophys. Res. Commun. 291 (2) :400-405 (2002) .

• Background Reference 02 :

  Woodring, P.J., et al., J. Biol. Chem. 272 (48) :30447-30454 (1997) .

• Background Reference 03 :

  Erneux, C., et al., Genomics 14 (2) :546-547 (1992) .

• Background Reference 04 :

  Takazawa, K., et al., Biochem. J. 272 (1) :107-112 (1990) .

• Other Product Names :

  Inositol-trisphosphate 3-kinase B, Inositol 1,5-trisphosphate 3-kinase B, IP3 3-kinase B, IP3K B, InsP 3-kinase B, ITPKB

• Tested Applications :

  WB, IHC-P, Flow

• Protein ID :

  62906885

• Physical Properties :

  Liquid