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ITPKB Antibody

CAT: 0223-63-442Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-63-442Size:400 µL
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Background
ITPKB regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins (1,3,4,5) P4. The activity of this encoded protein is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity.
NCBI Gene ID
3707
Swiss Prot
P27987
Accession Number
P27987
Host
Rabbit
Reactivity
Human
Immunogen
This ITPKB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 23-54 amino acids from the N-terminal region of human ITPKB.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
102 kDa
Fragment
Rabbit Ig
Symbol
ITPKB
NCBI Official Name
Inositol-trisphosphate 3-kinase B
NCBI Organism
Homo sapiens
Background Reference 01
Dewaste, V., et al., Biochem. Biophys. Res. Commun. 291 (2) :400-405 (2002) .
Background Reference 02
Woodring, P.J., et al., J. Biol. Chem. 272 (48) :30447-30454 (1997) .
Background Reference 03
Erneux, C., et al., Genomics 14 (2) :546-547 (1992) .
Background Reference 04
Takazawa, K., et al., Biochem. J. 272 (1) :107-112 (1990) .
Other Product Names
Inositol-trisphosphate 3-kinase B, Inositol 1,5-trisphosphate 3-kinase B, IP3 3-kinase B, IP3K B, InsP 3-kinase B, ITPKB
Tested Applications
WB, IHC-P, Flow
Protein ID
62906885
Physical Properties
Liquid

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