NM23 Antibody

• Background:

  NME1 was identified because of its reduced mRNA transcript levels in highly metastatic cells. NME1 encodes the 'A' isoform of nucleoside diphosphate kinase (NDK) . NDK exists as a hexamer composed of the 'A' (NME1) and 'B' (encoded by NME2) isoforms. Mutations in NME1 have been identified in aggressive neuroblastomas.

• NCBI Gene ID:

  4830

• Swiss Prot:

  P15531

• Accession Number:

  P15531

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This NM23 (NME1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-54 amino acids from the N-terminal region of human NM23 (NME1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  17 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  NME1

• NCBI Official Name:

  Nucleoside diphosphate kinase A

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Munier, A., et al., Exp. Cell Res. 289 (2) :295-306 (2003) .

• Background Reference 02:

  Chen, Y., et al., J. Mol. Biol. 332 (4) :915-926 (2003) .

• Background Reference 03:

  Kim, Y.I., et al., Biochem. Biophys. Res. Commun. 307 (2) :281-289 (2003) .

• Background Reference 04:

  Wang, P.H., et al., Gynecol. Obstet. Invest. 55 (1) :14-19 (2003) .

• Other Product Names:

  Nucleoside diphosphate kinase A, NDK A, NDP kinase A, Granzyme A-activated DNase, GAAD, Metastasis inhibition factor nm23, NM23-H1, Tumor metastatic process-associated protein, NME1, NDPKA, NM23

• Tested Applications:

  WB, IHC-P, IF

• Protein ID:

  127981

• Physical Properties:

  Liquid